New AI infrastructure startups in the US, October 2026
Updated October 31, 2026 · 54 first seen Jul 3 – Oct 1
54 new AI infrastructure startups were first seen online between July 3 and October 1, 2026. 18 of them appeared in the last 7 days of that window. These companies sell to large companies (27) and developers (26), with 1 aimed at consumers.
Seven of this month's AI infrastructure startups
| Startup | What it does | Where |
|---|---|---|
| System One Modelssystemonemodel.io | Provides open-source agent harness infrastructure and AI models for developers building decision systems. | San Francisco, CA |
| Omniraprivateomnira.com | Provides traceless computing infrastructure for AI inference across distributed machines. | Alameda, CA |
| ForgeVZforgevz.com | Provides virtual infrastructure and edge datacenter services to global customers. | US |
| Apera AIaperaai.ai | Offers a unified gateway for accessing multiple AI models with secure routing and cost control. | Palo Alto, CA |
| Valerius Cloudvaleriuscloud.com | Sells engineer-provisioned hosting, virtual servers and SSL certificates on AMD hardware to developers. | US |
| Mastrabuildonmastra.com | A TypeScript framework for developers to build and deploy AI agents and apps. | San Francisco, CA |
| Email for Agentsemailforagents.ai | Email API and MCP server letting AI agents manage inboxes with human approval. | CA |
47 more, with contact details, in FreshLeads.cc.
Start freeWho they sell to
| Large companies | 27 |
| Developers | 26 |
| Consumers | 1 |
Top cities
| San Francisco, CA | 10 |
| Miami, FL | 2 |
| New York, NY | 2 |
| Palo Alto, CA | 2 |
| Pasadena, CA | 1 |
| Los Angeles, CA | 1 |
California accounts for 19 of the 54, including 10 in San Francisco. Florida has 5 and New York has 3, followed by Colorado, Texas and Washington with 2 each.
More from FreshLeads
- New AI infrastructure startups in the US this week
- Other startup types: Hardware · Gaming · Green Tech · Music · AI · Tech
How we count: a business is listed when its website was first seen 30 to 120 days ago, it is in the US, and it shows a real business. We leave out personal sites and sensitive categories such as health care. We show the name, the website, the city and a description we write. We never show emails, phone numbers or people's names on this page. Full method.
Source: FreshLeads.cc analysis of 54 new US websites, October 2026. You may reuse the counts with credit (CC BY 4.0).
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